Vice President , Global Clinical Lead - Solid Tumor
Company: Takeda
Location: Boston
Posted on: January 7, 2026
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Job Description:
By clicking the “Apply” button, I understand that my employment
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information I provide in my application will be processed in line
with Takeda’s Privacy Notice and Terms of Use . I further attest
that all information I submit in my employment application is true
to the best of my knowledge. Job Description Are you looking for a
patient-focused, innovation-driven company that will inspire you
and empower you to shine? Join us as a Vice President , Global
Clinical Lead - Solid Tumor in our Cambridge office. At Takeda, we
are transforming the pharmaceutical industry through our
R&D-driven market leadership and being a values-led company. To
do this, we empower our people to realize their potential through
life-changing work. Certified as a Global Top Employer, we offer
stimulating careers, encourage innovation, and strive for
excellence in everything we do. We foster an inclusive,
collaborative workplace, in which our global teams are united by an
unwavering commitment to deliver Better Health and a Brighter
Future to people around the world. Here, you will be a vital
contributor to our inspiring, bold mission. OBJECTIVES :
Responsible for leading as the Global Clinical Lead a large solid
tumor oncology franchise that encompass multiple late stage and
early phase programs . Ensures ongoing review and agreement of the
Therapy Area Strategy and associated documents formulated by the
OTAU leader prior to their review and approval by appropriate
governance committees. Oversees the development and execution of
the Integrated Disease Area Strategy (IDAS) and overall Integrated
Global Development Plan (IGDP). Responsible for review of synopses,
other relevant clinical study documents and critical Study Results.
Provide leadership and oversight of specific OTAU related programs
and if applicable other indication specific clinical leads.
Responsible for providing guidance to TA leaders on regional
specificities within Therapeutic Area. ACCOUNTABILITIES: Clinical
Development team participation and leadership Accountable to
Oncology Clinical Science Head to provide strategic clinical input
on assigned clinical studies. Consistent with the Takeda R&D
Oncology Therapeutic Area Unit strategy, goals and objectives, this
leader will partner with the other key functions and leaders and
members of Oncology Precision and Translational Medicine, Oncology
Portfolio Strategy Group, Global Regulatory Affairs, Quantitative
and Clinical Pharmacology, other R&D Functional Line Oncology
Therapeutic Area Leads, Global Product Launch Strategy Oncology
Franchise Leads, Regional Oncology Franchise Leads, Oncology Drug
Development Unit (DDU) and other Oncology extended leadership, to
drive the alignment on global clinical research and development
strategy as related to internal and external pipeline and
non-pipeline initiatives for the Takeda R&D Oncology Community
across all regions Part of the Oncology Clinical Sciences
Leadership Team providing key input in strategic planning and
connectivity for the overall Oncology Clinical Sciences group Leads
the Global Development Team (US, EU, and others) managing both the
US/EU Development Team and the Japan/ China Development team for
assigned compounds. In some cases may lead the US/EU Development
Team but more likely will oversee the study physician and/or
clinical scientist leads responsible for leading the team. Emphasis
will be on insuring that the development teams are proactively
identifying contingencies, potential risks and strategies to
address future obstacles. Directs Development Team strategy and
deliverables overseeing the Development Strategy, Clinical
Development Plan and Clinical Protocols. Recommends scope,
complexity and size, which influence the budget of all aspects of a
program. Provides continual critical evaluation of the development
strategy to maintain a state-of-the-art development plan that is
competitive and consistent with the latest regulatory requirements,
proactive identification of challenges, and development of
contingency plans to meet them. Responsible for high impact global
decisions: interpreting data from ongoing internal and external
studies, assessing the medical and scientific implications and
making recommendations that impact regional and global development
such as “go/no go” decisions or modification of development plans
or study designs that may have a significant impact on timelines or
product labeling. Plans clinical development strategies in context
of medical/clinical significance considering how a given product
will fit in with current treatments, standard of care, and unmet
medical need. Accountable for ensuring regional strategies and
trade-offs in regional requirements are well articulated in the
global strategy documentation and that stakeholders are
appropriately briefed. Providing strategic input into global
development strategies and plans for all compounds in OTAU.
Providing clinical and strategic support to evaluation of external
compounds (alliances and in-licensing opportunities) Primary
interface with Medical Affairs team for strategy and to support of
product commercial efforts Contributing to the creation and
maintenance of regional KOL network Providing recommendations for
GDT leader nominations and reviewers of external compounds as part
of business development efforts Liaison with Clinical Operations
and Project Management for co-ordination of logistics study
planning and implementation Synopsis / Protocol Development, Study
Execution, & Study Interpretation Consistent with membership of the
Clinical Review Board Committee, responsible for critical review of
synopses, protocols, IBs and relevant clinical documents relating
to studies in assigned compounds. Trial Medical Monitoring Reviews
and assesses overall safety information in conjunction with
Pharmacovigilance and Medical Monitor of record for assigned
compounds. External Interactions Oversees and leads all clinical
science activities involved in interactions with FDA, other
regulatory agencies and key opinion leaders relevant to assigned
compounds. Responsible for evaluation of external interactions in
the context of overall development strategies using complex problem
solving in the region but in context of a global environment.
Proactive identification of challenges and development of
contingency plans as appropriate. Due Diligence, Business
Development and Alliance Projects Responsible for evaluation of
potential business development opportunities in the region but with
the context of a global environment. Conducts due diligence
evaluations, of clinical development plans for potential alliances
and or in-licensing opportunities. Serves as clinical contact point
for ongoing alliance projects and interface with partner to achieve
Takeda’s strategic goals while striving to maintain good working
relationship between Takeda and partner. Assigns and manages
clinical science staff who are involved in many of these
activities. Leadership, Task Force Participation, Upper Management
Accountability Interacts directly with research division based on
pertinent clinical and development expertise and in all aspects
relating to assigned compound in regional area. Leads TGRD internal
teams and global cross-functional teams. Works with functional
leadership to prioritize projects within the therapeutic area.
Hires, manages, mentors, motivates, empowers, develops and retains
staff to support assigned activities. Conducts performance reviews
and drive goal setting and development planning. EDUCATION,
EXPERIENCE, KNOWLEDGE AND SKILLS: Experience MD or combined MD/PhD
or internationally recognized equivalent with minimum 15 years
pharmaceutical research experience, including minimum 10 years late
phase clinical development experience with a focus on medical
oncology Clinical Training and Clinical Experience in
Hematology/Oncology and/or Medical Oncology especially in solid
tumor malignancies Strong depth of scientific and clinical
understanding and experience in cancer biology especially in immune
based therapies. Experience in conducting and/ or leading multiple
clinical trials involving immune based therapies Proven experience
in successfully leading and supervising direct reports including
several physicians, physician scientists, scientists within a
clinical development team in a global matrix environment.
Demonstrated ability to foster a high-performance culture and build
organizational capabilities. Strong leadership commitment to
diversity, equity and inclusion, with experience in creating an
inclusive and collaborative team environment that leverages diverse
perspectives. Previous experience in successfully leading several
clinical development team/matrix team with responsibility for
Global studies in multiple regions. Clinical Development experience
beyond US/EU Solid and Multiple experience in preparing and
interacting with multiple regulatory agencies including FDA, EMA,
and others Multiple NDA/MAA submission experience Proven ability to
lead and manage highly trained medical, scientific, and technical
professionals. Superior communication, strategic, interpersonal and
negotiating skills Enterprise level leadership with the ability to
inspire, motivate and drive results Excellent communication both
verbally and in writing and influencing skills, with the ability to
engage, inspire, and influence stakeholders at all levels,
including executive management and external partners. Ability to
proactively predict issues and solve problems Ability to drive
decision-making within a multi-disciplinary, multi-regional, matrix
teams Diplomacy and positive influencing abilities across
multinational business cultures TRAVEL REQUIREMENTS: Willingness to
travel to various meetings or client sites, including overnight
trips. Several international travels may be required. Requires
approximately 25-35 % travel. Takeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law This position is currently
classified as “hybrid” in accordance with Takeda’s Hybrid and
Remote Work policy. LI-JT1 Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider
the next step in your career. We are committed to equitable pay for
all employees, and we strive to be more transparent with our pay
practices. For Location: Boston, MA U.S. Base Salary Range:
$307,300.00 - $482,900.00 The estimated salary range reflects an
anticipated range for this position. The actual base salary offered
may depend on a variety of factors, including the qualifications of
the individual applicant for the position, years of relevant
experience, specific and unique skills, level of education
attained, certifications or other professional licenses held, and
the location in which the applicant lives and/or from which they
will be performing the job. The actual base salary offered will be
in accordance with state or local minimum wage requirements for the
job location. U.S. based employees may be eligible for short-term
and/ or long-term incentives. U.S. based employees may be eligible
to participate in medical, dental, vision insurance, a 401(k) plan
and company match, short-term and long-term disability coverage,
basic life insurance, a tuition reimbursement program, paid
volunteer time off, company holidays, and well-being benefits,
among others. U.S. based employees are also eligible to receive,
per calendar year, up to 80 hours of sick time, and new hires are
eligible to accrue up to 120 hours of paid vacation. EEO Statement
Takeda is proud in its commitment to creating a diverse workforce
and providing equal employment opportunities to all employees and
applicants for employment without regard to race, color, religion,
sex, sexual orientation, gender identity, gender expression,
parental status, national origin, age, disability, citizenship
status, genetic information or characteristics, marital status,
status as a Vietnam era veteran, special disabled veteran, or other
protected veteran in accordance with applicable federal, state and
local laws, and any other characteristic protected by law.
Locations Boston, MA Worker Type Employee Worker Sub-Type Regular
Time Type Full time Job Exempt Yes It is unlawful in Massachusetts
to require or administer a lie detector test as a condition of
employment or continued employment. An employer who violates this
law shall be subject to criminal penalties and civil liability.
Keywords: Takeda, Fall River , Vice President , Global Clinical Lead - Solid Tumor, Science, Research & Development , Boston, Massachusetts
