Sr. Manager, In Silico First Program & Strategy Management

Company: Takeda
Location: Boston
Posted on: January 1, 2026

Job Description:

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Pursuant to Section 20 C.F.R. 656.10, you are hereby notified that an application for Alien Employment Certification will be filed by Takeda Development Center Americas, Inc. for the following job opportunity: JOB LOCATION: Cambridge, MA POSITION : Sr. Manager, In Silico First Program & Strategy Management POSITION DESCRIPTION : Takeda Development Center Americas, Inc. is seeking a Sr. Manager, In Silico First Program & Strategy Management with the following duties: independently manage roadmaps and strategic plans to advance the ISF program, in alignment with company goals and objectives; oversee day-to-day operations of the initiative, ensuring smooth execution and timely delivery of projects; collaborate with and influence stakeholders, including the PharmSci Capability Owners in the global suites as well as the local functional teams to ensure initiative alignment and scalability across the global framework; foster cross-functional collaboration to drive the adoption of innovative methodologies while maintaining regulatory compliance where only recent guidance is available and is evolving; establish and monitor performance metrics to gauge the success and ROI of the ISF roadmap and ensure alignment with strategic business goals; lead resource planning, budget management, and timelines across Pharm Sci functional areas; manage with close support external vendor partnerships to enhance execution & scalability of PSST initiatives; support Change Management efforts to facilitate smooth transitions to new processes & technologies, ensuring stakeholder engagement & minimizing disruptions; drive strategic communication efforts to ensure clear understanding and support of the In Silico First paradigm by and across the organization; provide technical expertise in in silico model development, ensuring the application of best practices and cutting-edge methodologies; serve as an embedded in silico Subject Matter expert in select lighthouse projects; drive the development and validation of computational models, leveraging deep expertise in silico approaches; ensure the integration of in silico models with experimental data and workflows to enhance predictive accuracy and reliability and ensure increased productivity. Up to 10% international travel required to attend business meetings, subject matter consultation, and visit local sites for program oversight. Up to 75% remote work permitted. REQUIREMENTS: Ph.D. in Pharmacy and Biomedical Sciences or related field, plus 2 years of related experience. Prior experience must include: contribute to the creating of global strategic roadmaps and frameworks (such as the Pharm Sci Digital Strategy and R&D Integrated Digital Strategy, while effectively managing project timelines and deliverables, planning and coordinating projects with departmental, functional, and external stakeholders; lead change management strategy for In Silico First and Aedifica Fortis, managing close collaboration with external vendors to enhance execution of these strategies; oversee day-to-day operations of the Aedifica fortis portfolio for Pharm Sci, ensuring strategic alignment, successful execution and timely delivery of projects; drive technical projects for the In Silico First initiative, which integrates in silico models with experimental data and workflows to enhance predictive accuracy and reliability to ensure increased productivity and reduced resource and time consumption. Full time. $137,000 to $234,800 per year. Qualified applicants can apply at https://jobs.takeda.com . Please reference job R0170037. EOE Any individual may provide documentary evidence bearing on this application, with information on available workers and information on wages and working conditions, to the Certifying Officer, U.S. Department of Labor, Employment and Training Administration, Office of Foreign Labor Certification, 200 Constitution Avenue, NW, Room N-5311, Washington, DC 20210. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time

Keywords: Takeda, Fall River , Sr. Manager, In Silico First Program & Strategy Management, IT / Software / Systems , Boston, Massachusetts